Cell Biology Program
The Lydia Finley Lab
Research
The Finley Lab investigates how cellular metabolic pathways regulate cell fate decisions in stem cells and cancer cells. We combine genetic and metabolomic approaches to investigate cell-type specific growth requirements and elucidate how flux through central metabolic pathways regulates key cellular activities, including self-renewal and differentiation. In particular, we are interested in understanding how changes in metabolite availability shape the chromatin landscape to influence gene expression programs that control cell survival, growth and differentiation. Our work aims to answer fundamental questions about how cells regulate the commitment to differentiation and how failure to execute terminal differentiation can underlie diseases such as cancer.
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People
Lydia Finley, PhD
Geoffrey Beene Junior Faculty Chair
- Lydia Finley studies the mechanisms that link metabolic pathways to cell fate decisions.
- PhD, Harvard University
- BS, Yale University
- [email protected]
- Email Address
- 212-639-6722
- Office Phone
Members
Research Associate
Research Fellow
Graduate Student
Graduate Student
Graduate Student
Graduate Student
MSK Bridge Program Scholar
Research Fellow
Sr. Administrative Assistant
Lab Alumni
Postdoctoral Associate at Rockefeller University, New York, NY
Research Technician
Graduate Student
Medical Resident
Graduate Research Assistant
Lab Affiliations
Achievements
- New York Stem Cell Foundation – Robertson Investigator (2023)
- Louise and Allston Boyer Young Investigator Award for Basic Research (2022)
- National Cancer Institute R37 MERIT Award (2020)
- Pershing Square Sohn Prize for Cancer Research (2020)
- Searle Scholar (2018)
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- Dale F. Frey Breakthrough Award of the Damon Runyon Cancer Research Foundation (2017)